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Lecture Notes

Table for Lecture Notes
LEC #	TOPICS	LECTURERS	LecTURE noTES
I. Unit Cell Processes and Mechanics of Matrix Molecules and Tissues Structures
1	Clinical Examples of the Roles of Mechanical Forces in Tissues and Organs: The Working Paradigms	Prof. Spector	(PDF)
2	Tissue Structures and Unit Cell Processes	Prof. Spector	(PDF 1) (PDF 2) (PDF 3)
3	Cell-Matrix Interactions: Extracellular Matrix Molecules, Adhesion Proteins and Integrins	Prof. Spector	(PDF 1) (PDF 2)
4	Models for the Mechanical Behavior of Porous Scaffolds	Prof. L. Gibson	(PDF)
5	Structure-Properties Relationships for Tissues	Prof. Spector
6	Mechanics of Selected Tissues	Prof. S. Socrate
II. Mechanics of Cells: Effects of Exogenous Forces and Endogenous Force Generation
7	Effects of Exogenous Mechanical Forces on Cells	Prof. Spector
8	Response of Cells to Substrate Strain	Prof. Spector	(PDF)
9	Endothelial Cell Response to Flow	Prof. C. F. Dewey
10	Quiz 1
11	Measuring Cell Contraction Cell Force Monitor	Brendan Harley	(PDF)
12	Endogenous Mechanical Force Generation by Cells	Prof. Spector	(PDF 1) (PDF 2)
13	Models for Cell Contraction In Vitro and In Vivo	Prof. Spector	(PDF 1) (PDF 2)
14	Mechanical Coupling of Cells with Matrix	Prof. Yannas	(PDF 1) (PDF 2)
15	Cell-matrix Interactions During Wound Closure	Prof. Yannas	(PDF - 1.6 MB)
16	Blockade of Contraction During Induced Organ Regeneration	Prof. Yannas	(PDF - 1.6 MB)
17	Review	Prof. Spector
18	Quiz 2
III. Tissue Mechanics
19	Review of Principles of Linear Elastic Mechanics	Prof. Yannas	(PDF - 1.1 MB)
20	Nonlinear Elasticity: Tendon and Skin	Prof. Yannas	(PDF)
21	Linear Viscoelastic Behavior	Prof. Yannas	(PDF - 1.0 MB)
22	Response of Articular Cartilage to Mechanical Loading	Prof. A. Grodzinsky
23	Mechanical Behavior of Ligament, Meniscus and Intervertebral Disc	Prof. Spector	(PDF 1) (PDF 2)
24	Mechanical Behavior of Bone	Prof. Spector	(PDF)
25	Response of Bone to Mechanical Loading Review	Prof. Spector	(PDF)
26	Quiz 3